Development and Validation of HPLC Method for the Quantification of Atorvastatin in Pharmaceutical Dosage Forms and Biological Fluid

<p>A<strong> </strong>reverse phase HPLC method was developed for the determination of atorvastatin. The mobile phase involved for the separation was phosphate buffer and acetonitrile with a ratio of 10:1. The HPLC column C₁₈ ODS hypersil column (250 mm×4.6 mm, 5 μm) was used and detected at 215 nm. The run time of the current method was 5 minutes with excellent specificity; no interferences were observed...