Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke

Importance

Prior trials of dual antiplatelet therapy excluded patients with moderate ischemic stroke. These patients were included in the Acute Stroke or Transient Ischaemic Attack Treated With Ticagrelor and ASA for Prevention of Stroke and Death (THALES) trial, but results have not been reported separately, raising concerns about safety and efficacy in this subgroup.

Objective

To evaluate the efficacy and safety of ticagrelor...