Apoptotic cell signals and heterogeneity in macrophage function: Fine-tuning for a healthy liver
Abstract
Functional heterogeneity in tissue macrophage populations has often been traced to developmental and spatial cues. Upon tissue damage, macrophages are exposed to soluble mediators secreted by activated cells, which shape their polarisation. Interestingly, macrophages are concomitantly exposed to a variety of different dying cells, which carry miscellaneous signals and that need to be recognised and promptly up-taken by professional phagocytes....
Paper Details
Title
Apoptotic cell signals and heterogeneity in macrophage function: Fine-tuning for a healthy liver
Published Date
Nov 1, 2021
Volume
119
Pages
72 - 81
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Notes
History