PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology

Volume: 9, Issue: 7, Pages: 793 - 793
Published: Jul 8, 2021
Abstract
Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells. PCSK9 has been known to interact with the low-density lipoprotein receptor (LDLR) and chaperones the receptor to its degradation. In this manner, targeting PCSK9 is a novel attractive approach to reduce hyperlipidaemia and the risk for cardiovascular diseases....
Paper Details
Title
PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology
DOI
Published Date
Jul 8, 2021
Journal
Volume
9
Issue
7
Pages
793 - 793
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