Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
Abstract
Archived formalin-fixed paraffin-embedded (FFPE) samples are the global standard format for preservation of the majority of biopsies in both basic research and translational cancer studies, and profiling chromatin accessibility in the archived FFPE tissues is fundamental to understanding gene regulation. Accurate mapping of chromatin accessibility from FFPE specimens is challenging because of the high degree of DNA damage. Here, we first showed...
Paper Details
Title
Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
Published Date
Jul 14, 2021
Journal
Volume
32
Issue
1
Pages
150 - 161
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History