Short-term Bed Rest Exposure Impairs Peripheral Vascular And Endothelial Functions Whereas Mitochondrial Respiration Is Unaffected

PURPOSE: Impairments of oxidative metabolism after exposure to microgravity are documented, but the sites of impairment are still debated. Aim of this study was to identify markers of impaired oxidative metabolism along the O2 pathway, following 10-day of horizontal bed rest (BR). METHODS: fore (PRE) and after (POST) BR, 10 young males performed on a cycle ergometer an incremental exercise (to determine peak pulmonary V̇O2 [V̇O2p] and peak...