PCL-TPGS polymeric nanoparticles for docetaxel delivery to prostate cancer: Development, physicochemical and biological characterization

Giovanni Loureiro Raspantini; Marcela Tavares Luiz; Juliana Palma Abriata; Josimar O. Eloy; Miguel Menezes Vaidergorn; Flavio da Silva Emery; Juliana Maldonado Marchetti

doi:https://doi.org/10.1016/j.colsurfa.2021.127144

doi.org/10.1016/j.colsurfa.2021.127144

PCL-TPGS polymeric nanoparticles for docetaxel delivery to prostate cancer: Development, physicochemical and biological characterization

Giovanni Loureiro Raspantini

5

,

Marcela Tavares Luiz

10

,

..., Juliana Maldonado Marchetti

25

Colloids and Surfaces A: Physicochemical and Engineering Aspects5.20

Volume: 627, Pages: 127144 - 127144

Published: Oct 1, 2021

Abstract

Prostate cancer is the second most common type of cancer in men, remaining the second leading cause of cancer-related deaths in this gender. In order to improve the security and efficacy of its treatment, nanostructured delivery systems have been widely studied. The present work aimed to develop and characterize polymeric nanoparticles based on a copolymer of polycaprolactone-DL-α-tocopherol-polyethylene glycol-1000 (PCL-block-TPGS) containing...

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Paper Details

Title

PCL-TPGS polymeric nanoparticles for docetaxel delivery to prostate cancer: Development, physicochemical and biological characterization

DOI

doi.org/10.1016/j.colsurfa.2021.127144

Published Date

Oct 1, 2021

Journal

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volume

627

Pages

127144 - 127144

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