Influence of cysteine-directed mutations at the Ω-loops on peroxidase activity of human cytochrome c

Volume: 709, Pages: 108980 - 108980
Published: Sep 1, 2021
Abstract
Cytochrome c (Cytc) is a multifunctional protein associated with electron shuttling in the inner membrane of mitochondria and also involving in the apoptotic pathway. It has been identified that mutations located in the flexible central 40-57 Ω-loop including the naturally occurring G41S, Y48H, and A51V mutants, which are found in patients with thrombocytopenia 4, a platelet disorder, alter the structural properties of human Cytc (hCytc) that...
Paper Details
Title
Influence of cysteine-directed mutations at the Ω-loops on peroxidase activity of human cytochrome c
Published Date
Sep 1, 2021
Volume
709
Pages
108980 - 108980
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