Potential alternatives to current cholinesterase inhibitors: an in silico drug repurposing approach

Volume: 47, Issue: 6, Pages: 919 - 930
Published: Jun 3, 2021
Abstract
Acetylcholinesterase/Butyrylcholinesterase inhibitors are considered an effective method for treating Alzheimer’s disease (AD). In this current work, we have computationally analyzed 11 new small molecule drugs used in various neurological diseases and Donepezil, a known inhibitor of acetylcholinesterase, as a positive control. We investigated these drugs for possible fundamental interactions with acetylcholinesterase and butyrylcholinesterase...
Paper Details
Title
Potential alternatives to current cholinesterase inhibitors: an in silico drug repurposing approach
Published Date
Jun 3, 2021
Volume
47
Issue
6
Pages
919 - 930
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