Can TP53-mutant follicular adenoma be a precursor of anaplastic thyroid carcinoma?
Abstract
Mutations of the TP53 tumor suppressor gene are highly prevalent in thyroid anaplastic carcinomas (AC) but are also reported in some well-differentiated cancers and even in benign adenomas. The natural history of TP53-mutant adenomas and whether they may represent a precursor for well-differentiated cancer or AC is largely unknown. Similarly, the frequency of TP53 mutations in thyroid nodules found on routine molecular analysis of fine-needle...
Paper Details
Title
Can TP53-mutant follicular adenoma be a precursor of anaplastic thyroid carcinoma?
Published Date
Sep 1, 2021
Journal
Volume
28
Issue
9
Pages
621 - 630
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Notes
History