ATG9A protects the plasma membrane from programmed and incidental permeabilization
Abstract
The integral membrane protein ATG9A plays a key role in autophagy. It displays a broad intracellular distribution and is present in numerous compartments, including the plasma membrane (PM). The reasons for the distribution of ATG9A to the PM and its role at the PM are not understood. Here, we show that ATG9A organizes, in concert with IQGAP1, components of the ESCRT system and uncover cooperation between ATG9A, IQGAP1 and ESCRTs in protection...
Paper Details
Title
ATG9A protects the plasma membrane from programmed and incidental permeabilization
Published Date
Jul 12, 2021
Journal
Volume
23
Issue
8
Pages
846 - 858
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