New insights into the mechanisms of age-related protein-protein crosslinking in the human lens

Volume: 209, Pages: 108679 - 108679
Published: Aug 1, 2021
Abstract
Although protein crosslinking is often linked with aging as well as some age-related diseases, very few molecular details are available on the nature of the amino acids involved, or mechanisms that are responsible for crosslinking. Recent research has shown that several amino acids are able to generate reactive intermediates that ultimately lead to covalent crosslinking through multiple non-enzymatic mechanisms. This information has been derived...
Paper Details
Title
New insights into the mechanisms of age-related protein-protein crosslinking in the human lens
Published Date
Aug 1, 2021
Volume
209
Pages
108679 - 108679
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