A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium
Abstract
The United States Environmental Protection Agency (US EPA) recently developed a tiered testing strategy to use advances in high-throughput transcriptomics (HTTr) testing to identify molecular targets of thousands of environmental chemicals that can be linked to adverse outcomes. Here, we describe a method that uses a gene expression biomarker to predict chemical activation of heat shock factor 1 (HSF1), a transcription factor critical for...
Paper Details
Title
A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium
Published Date
Jun 25, 2021
Volume
34
Issue
7
Pages
1721 - 1737
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