Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas.
Abstract
Despite significant progress in the treatment of patients with diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL), prognosis of patients with relapsed disease remains poor due to the emergence of drug resistance and subsequent disease progression. Identification of novel targets and therapeutic strategies for these diseases represents an urgent need. Here, we report that both MCL and DLBCL are exquisitely sensitive to...
Paper Details
Title
Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas.
Published Date
Jun 24, 2021
Journal
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Notes
History