Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

Volume: 31, Pages: 102740 - 102740
Published: Jan 1, 2021
Abstract
Adults with Down syndrome are genetically predisposed to develop Alzheimer's disease and accumulate beta-amyloid plaques (Aβ) early in life. While Aβ has been heavily studied in Down syndrome, its relationship with neurofibrillary tau is less understood. The aim of this study was to evaluate neurofibrillary tau deposition in individuals with Down syndrome with varying levels of Aβ burden.A total of 161 adults with Down syndrome (mean age = 39.2...
Paper Details
Title
Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome
Published Date
Jan 1, 2021
Volume
31
Pages
102740 - 102740
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