Candidate l‐methionine target piRNA regulatory networks analysis response to cocaine‐conditioned place preference in mice

Background Methionine has been proven to inhibit addictive behaviors of cocaine dependence. However, the mechanism of methionine response to cocaine CPP is unknown. Recent evidence highlights piRNAs to regulate genes via a miRNA‐like mechanism. Here, next‐generation sequencing is used to study mechanism on methionine response to drug‐induced behaviors though piRNA. Methods l ‐methionine treatment cocaine CPP animal model was used to do...