CLec-TM1–ERK–GSK3β Pathway Regulates Vibrio splendidus–Induced IL-17 Production in Oyster

C-type lectins are a family of pattern recognition receptors that recognize microbial components and subsequently activate the signaling cascade to induce the production of proinflammatory cytokines. In the current study, the homologs of ERK (named as CgERK) and GSK3β (named as CgGSK3β) and a novel C-type lectin with a transmembrane domain (named as CgCLec-TM1) were identified from oyster Crassostrea gigasCgCLec-TM1 was able to bind Escherichia...