pH-responsive core-shell nanogels induce in situ antigen production for cancer treatment
Abstract
Chemo-immunotherapy has the superiority of remedying malignant and metastatic tumors, and acquiring better therapeutic effect as well as prognosis than monotherapy. Herein, we report a kind of pH-responsive core-shell nanoparticles to achieve the co-delivery of oxaliplatin intermediate (oxa im) (HCLO NPs) and cytosine-guanine containing oligodeoxynucleotides (CpG) for cancer treatment. The nanoparticles comprise the core of lipid-coated calcium...
Paper Details
Title
pH-responsive core-shell nanogels induce in situ antigen production for cancer treatment
Published Date
Dec 1, 2021
Journal
Volume
426
Pages
130839 - 130839
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