Beyond CGRP: The calcitonin peptide family as targets for migraine and pain
Abstract
The CGRP system has emerged as a key pharmacological target for the treatment of migraine. However, some individuals who suffer from migraine have low or no response to anti-CGRP or other treatments, suggesting the need for additional clinical targets. CGRP belongs to the calcitonin family of peptides, which includes calcitonin, amylin, adrenomedullin and adrenomedullin 2. These peptides display a range of pro-nociceptive and anti-nociceptive...
Paper Details
Title
Beyond CGRP: The calcitonin peptide family as targets for migraine and pain
Published Date
Jul 27, 2021
Volume
179
Issue
3
Pages
381 - 399
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