Chemical probes for tagging mycobacterial lipids
Abstract
Mycobacteria, which cause tuberculosis and related diseases, possess a diverse set of complex envelope lipids that provide remarkable tolerance to antibiotics and are major virulence factors that drive pathogenesis. Recently, metabolic labeling and bio-orthogonal chemistry have been harnessed to develop chemical probes for tagging specific lipids in live mycobacteria, enabling a range of new basic and translational research avenues. A toolbox of...
Paper Details
Title
Chemical probes for tagging mycobacterial lipids
Published Date
Dec 1, 2021
Volume
65
Pages
57 - 65
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