Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction

Volume: 49, Issue: 17, Pages: e102 - e102
Published: Jul 2, 2021
Abstract
Rapidly evolving RNA viruses continuously produce minority haplotypes that can become dominant if they are drug-resistant or can better evade the immune system. Therefore, early detection and identification of minority viral haplotypes may help to promptly adjust the patient's treatment plan preventing potential disease complications. Minority haplotypes can be identified using next-generation sequencing, but sequencing noise hinders accurate...
Paper Details
Title
Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction
Published Date
Jul 2, 2021
Volume
49
Issue
17
Pages
e102 - e102
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