Demystifying particle-based oral vaccines

Volume: 18, Issue: 10, Pages: 1455 - 1472
Published: Jul 6, 2021
Abstract
Introduction: The oral route of vaccination is pain- and needle-free and can induce systemic and mucosal immunity. However, gastrointestinal barriers and antigen degradation impose significant hurdles in the development of oral vaccines. Live attenuated viruses and bacteria can overcome these barriers but at the risk of introducing safety concerns. As an alternative, particles have been investigated for antigen protection and delivery, yet there...
Paper Details
Title
Demystifying particle-based oral vaccines
Published Date
Jul 6, 2021
Volume
18
Issue
10
Pages
1455 - 1472
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