Evolutionary selectivity of amino acid is inspired from the enhanced structural stability and flexibility of the folded protein
Abstract
The present study attempts to decipher the site-specific amino acid alterations at certain positions experiencing preferential selectivity and their effect on proteins' stability and flexibility. The study examines the selection preferences by considering pair-wise non-bonded interaction energies of adjacent and interacting amino acids present at the interacting site, along with their evolutionary history. For the study, variations in the...
Paper Details
Title
Evolutionary selectivity of amino acid is inspired from the enhanced structural stability and flexibility of the folded protein
Published Date
Sep 1, 2021
Journal
Volume
281
Pages
119774 - 119774
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Notes
History