The Type IV Collagenase Inhibitor, BiPS, Alters Keratin Expression in Sulfur Mustard Exposed Mouse Skin
Abstract
Sulfur mustard (SM) is a potent chemical vesicant targeting many tissues including skin. The SM induced cutaneous toxicity is associated with edema, epidermal erosions, inflammation, and prolonged wound repair. Earlier studies have shown that overexpression of matrix metalloproteinase 9 (MMP9) degrades extracellular matrix proteins and leads to the separation of epidermis from dermis in skin exposed to SM. We have found that MMP9, a type IV...
Paper Details
Title
The Type IV Collagenase Inhibitor, BiPS, Alters Keratin Expression in Sulfur Mustard Exposed Mouse Skin
Published Date
Apr 1, 2019
Journal
Volume
33
Issue
S1
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