Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children.
Abstract
Children have reduced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates and a substantially lower risk for developing severe coronavirus disease 2019 compared with adults. However, the molecular mechanisms underlying protection in younger age groups remain unknown. Here we characterize the single-cell transcriptional landscape in the upper airways of SARS-CoV-2-negative (n = 18) and age-matched SARS-CoV-2-positive...
Paper Details
Title
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children.
Published Date
Aug 18, 2021
Journal
Pages
1 - 6
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Notes
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