DYF-4 regulates patched-related/DAF-6-mediated sensory compartment formation in C. elegans
Abstract
Coordination of neurite extension with surrounding glia development is critical for neuronal function, but the underlying molecular mechanisms remain poorly understood. Through a genome-wide mutagenesis screen in C. elegans, we identified dyf-4 and daf-6 as two mutants sharing similar defects in dendrite extension. DAF-6 encodes a glia-specific patched-related membrane protein that plays vital roles in glial morphogenesis. We cloned dyf-4 and...
Paper Details
Title
DYF-4 regulates patched-related/DAF-6-mediated sensory compartment formation in C. elegans
Published Date
Jun 11, 2021
Journal
Volume
17
Issue
6
Pages
e1009618 - e1009618
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