Secretin activates brown fat and induces satiation
Abstract
Brown adipose tissue (BAT) thermogenesis is activated by feeding. Recently, we revealed a secretin-mediated gut-BAT-brain axis, which stimulates satiation in mice, but the purpose of meal-induced BAT activation in humans has been unclear. In this placebo-controlled, randomized crossover study, we investigated the effects of intravenous secretin on BAT metabolism (measured with [18F]FDG and [15O]H2O positron emission tomography) and appetite...
Paper Details
Title
Secretin activates brown fat and induces satiation
Published Date
Jun 21, 2021
Journal
Volume
3
Issue
6
Pages
798 - 809
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