Early Β-Amyloid Accumulation in the Brain Is Associated With Blood T and B Cell Alterations

Published: Jun 17, 2021
Abstract
Fast and minimally invasive approaches for early, preclinical diagnosis of neurodegenerative Alzheimer’s disease (AD) are highly anticipated. Evidence of adaptive immune cells responding to cerebral β-amyloidosis, one of the pathological hallmarks of AD, has raised the question of whether immune markers could be used as proxies for β-amyloid accumulation in the brain. Here, we deploy multidimensional mass cytometry combined with unbiased machine...
Paper Details
Title
Early Β-Amyloid Accumulation in the Brain Is Associated With Blood T and B Cell Alterations
Published Date
Jun 17, 2021
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