Dynamic cardiac PET motion correction using 3D normalized gradient fields in patients and phantom simulations

This work expands on the implementation of three‐dimensional (3D) normalized gradient fields to correct for whole‐body motion and cardiac creep in [N‐13]‐ammonia patient studies and evaluates its accuracy using a dynamic phantom simulation model. Methods A full rigid‐body algorithm was developed using 3D normalized gradient fields including a multi‐resolution step and sampling off the voxel grid to reduce interpolation artifacts. Optimization...