Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice

Volume: 11, Issue: 1, Pages: 13021
Published: Jun 22, 2021
Abstract
A syngeneic mouse model bearing a transplanted tumor is indispensable for the evaluation of the efficacy of immune checkpoint inhibitors (ICIs). However, few syngeneic mouse models of liver cancer are available. We established liver tumor cell lines (MHCF1 and MHCF5) from hepatitis C virus transgenic mice fed an atherogenic high-fat diet. MHCF1 and MHCF5 were successfully transplanted into the subcutaneous space of syngeneic C57BL/6 mice, in...
Paper Details
Title
Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice
Published Date
Jun 22, 2021
Volume
11
Issue
1
Pages
13021
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