Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer
Abstract
Background The presence of hypoxia is a poor prognostic factor in prostate cancer and the hypoxic tumor microenvironment promotes radioresistance. There is potential for drug radiotherapy combinations to improve the therapeutic ratio. We aimed to investigate whether hypoxia-associated genes could be used to identify FDA approved drugs for repurposing for the treatment of hypoxic prostate cancer. Methods Hypoxia associated genes were identified...
Paper Details
Title
Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer
Published Date
Jul 1, 2021
Journal
Volume
21
Issue
1
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