Integrin αvβ6-targeted MR molecular imaging of breast cancer in a xenograft mouse model
Abstract
Background The motif RXDLXXL-based nanoprobes allow specific imaging of integrin α v β 6 , a protein overexpressed during tumorigenesis and tumor progression of various tumors. We applied a novel RXDLXXL-coupled cyclic arginine-glycine-aspartate (RGD) nonapeptide conjugated with ultrasmall superparamagnetic iron oxide nanoparticles (referred to as cFK-9-USPIO) for the application of integrin α v β 6 -targeted magnetic resonance (MR) molecular...
Paper Details
Title
Integrin αvβ6-targeted MR molecular imaging of breast cancer in a xenograft mouse model
Published Date
Jun 29, 2021
Journal
Volume
21
Issue
1
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