Pharmacokinetics of yunaconitine and indaconitine in mouse blood by UPLC-MS/MS
Abstract
• First reported of bioavailability of yunaconitine and indaconitine in mice. • First reported UPLC-MS/MS method for the measurement of yunaconitine and indaconitine in vivo . • The method only required 20 µL of treated blood for accurate analysis. Yunaconitine and indaconitine are active ingredients from the rhizomes of Aconitum plants. In this study, an ultra-high-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method...
Paper Details
Title
Pharmacokinetics of yunaconitine and indaconitine in mouse blood by UPLC-MS/MS
Published Date
Aug 1, 2021
Journal
Volume
1179
Pages
122840 - 122840
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