The role of ADAM17 during liver damage
Abstract
A disintegrin and metalloprotease (ADAM) 17 is a membrane bound protease, involved in the cleavage and thus regulation of various membrane proteins, which are critical during liver injury. Among ADAM17 substrates are tumor necrosis factor α (TNFα), tumor necrosis factor receptor 1 and 2 (TNFR1, TNFR2), the epidermal growth factor receptor (EGFR) ligands amphiregulin (AR) and heparin-binding-EGF-like growth factor (HB-EGF), the interleukin-6...
Paper Details
Title
The role of ADAM17 during liver damage
Published Date
Jun 30, 2021
Journal
Volume
402
Issue
9
Pages
1115 - 1128
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