Programmed death-1 mediates venous neointimal hyperplasia in humans and rats
Abstract
Venous neointimal hyperplasia can be a problem after vein interventions. We hypothesized that inhibiting programmed death-1 (PD-1) can decrease venous neointimal hyperplasia in a rat inferior vena cava (IVC) patch venoplasty model. The rats were divided into four groups: the control group was only decellularized without other special treatment; the PD-1 group was injected with a single dose of humanized PD-1 antibody (4 mg/kg); the PD-1 antibody...
Paper Details
Title
Programmed death-1 mediates venous neointimal hyperplasia in humans and rats
Published Date
Jun 24, 2021
Journal
Volume
13
Issue
12
Pages
16656 - 16666
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