Silencing of circTASP1 inhibits proliferation and induces apoptosis of acute myeloid leukaemia cells through modulating miR‐515‐5p/HMGA2 axis

Volume: 25, Issue: 15, Pages: 7367 - 7380
Published: Jul 1, 2021
Abstract
Acute myeloid leukaemia (AML) is a common hematopoietic disease that is harmful to the lives of children and adults. CircRNAs are aberrantly expressed in the haematologic malignancy cells. However, the expression of circTASP1 and its function in AML remain unclear. In this study, we showed that circTASP1 was significantly up-regulated in AML peripheral blood samples and cells. Knockdown of circTASP1 inhibited proliferation and promoted apoptosis...
Paper Details
Title
Silencing of circTASP1 inhibits proliferation and induces apoptosis of acute myeloid leukaemia cells through modulating miR‐515‐5p/HMGA2 axis
Published Date
Jul 1, 2021
Volume
25
Issue
15
Pages
7367 - 7380
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