Evaluation of the anti-Toxoplasma gondii Activity of Hederagenin in vitro and in vivo
Abstract
Toxoplasma gondii infection is widespread worldwide, not only posing a serious threat to human food safety and animal husbandry, but also endangering human health. The selectivity index was employed to measure anti-T. gondii activity. Hederagenin (HE) exhibited potent anti-T. gondii activity and low cytotoxicity. For this reason, HE was selected for in vivo experiments. HE showed 64.8%±13.1% inhibition for peritoneal tachyzoites in mice, higher...
Paper Details
Title
Evaluation of the anti-Toxoplasma gondii Activity of Hederagenin in vitro and in vivo
Published Date
Jun 21, 2021
Volume
59
Issue
3
Pages
297 - 301
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