Polydopamine-based biofunctional substrate coating promotes mesenchymal stem cell migration
Abstract
Rapid migration of mesenchymal stem cells (MSCs) on device surfaces could support in vivo tissue integration and might facilitate in vitro organoid formation. Here, polydopamine (PDA) is explored as a biofunctional coating to effectively promote MSC motility. It is hypothesized that PDA stimulates fibronectin deposition and in this way enhances integrin-mediated migration capability. The random and directional cell migration was investigated by...
Paper Details
Title
Polydopamine-based biofunctional substrate coating promotes mesenchymal stem cell migration
Published Date
Jun 30, 2021
Journal
Volume
6
Issue
31
Pages
739 - 744
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