Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
Abstract
Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclinical studies, clinical trial results have been disappointing. A greater understanding of the mechanisms through which antioxidants act and where and when they are effective may provide a rational...
Paper Details
Title
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
Published Date
Jun 30, 2021
Volume
20
Issue
9
Pages
689 - 709
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