Determination of amoxicillin and cotrimoxazole concentrations in sputum of patients with cystic fibrosis.
Abstract
In the management of cystic fibrosis, treatments against Staphylococcus aureus and Haemophilus influenzae such as amoxicillin or cotrimoxazole have to be prescribed and the antibiotherapy's efficacy may be linked to the concentration that reaches the infected site. As cystic fibrosis patients present disturbed pharmacokinetics parameters, drug monitoring would be relevant to assess the lung distribution of antibiotics and to optimize dosing...
Paper Details
Title
Determination of amoxicillin and cotrimoxazole concentrations in sputum of patients with cystic fibrosis.
Published Date
Dec 1, 2021
Journal
Volume
35
Issue
12
Pages
e5208 - e5208
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Notes
History