Inflammatory cell death induced by cytotoxic lymphocytes: a dangerous but necessary liaison

Volume: 289, Issue: 15, Pages: 4398 - 4415
Published: Jul 17, 2021
Abstract
Cytotoxic lymphocytes (CLs), and more specifically Tc and NK cells, are the main executors of cell death in the immune system, playing a key role during both immunosurveillance and immunotherapy. These cells induce regulated cell death (RCD) by different mechanisms, being granular exocytosis and expression of death ligands the most prominent and best characterized ones. Apoptosis, a traditionally considered low-inflammatory type of cell death,...
Paper Details
Title
Inflammatory cell death induced by cytotoxic lymphocytes: a dangerous but necessary liaison
Published Date
Jul 17, 2021
Journal
Volume
289
Issue
15
Pages
4398 - 4415
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