Organotypic 3D decellularized matrix tumor spheroids for high-throughput drug screening
Abstract
Decellularized extracellular matrix (dECM) is emerging as a valuable tool for generating 3D in vitro tumor models that better recapitulate tumor-stroma interactions. However, the development of dECM-3D heterotypic microtumors exhibiting a controlled morphology is yet to be materialized. Precisely controlling microtumors morphologic features is key to avoid an inaccurate evaluation of therapeutics performance during preclinical screening. To...
Paper Details
Title
Organotypic 3D decellularized matrix tumor spheroids for high-throughput drug screening
Published Date
Aug 1, 2021
Journal
Volume
275
Pages
120983 - 120983
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