Transient Permeation Enhancer® (TPE®) technology for oral delivery of octreotide: a technological evaluation
Abstract
The FDA approval of oral semaglutide for type 2 diabetes (2019) and oral octreotide for acromegaly (2020) is evidence that selected niche peptides can be administered orally if formulated with selected intestinal permeation enhancers.We evaluated the oral octreotide formulation, MYCAPSSA® (Chiasma Pharmaceuticals, Needham, MA, USA). An outline of the current standard of care in acromegaly and the benefits of oral octreotide versus depot...
Paper Details
Title
Transient Permeation Enhancer® (TPE®) technology for oral delivery of octreotide: a technological evaluation
Published Date
Jun 28, 2021
Volume
18
Issue
10
Pages
1501 - 1512
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