Engineering collagen fiber templates with oriented nanoarchitecture and concerns on osteoblast behaviors

Nanostructure provides a closer structural support approximation to native bone architecture for cells and further regulates cell's behavior, resulting in the formation of functional tissues. In this work, three engineering collagen templates with oriented fiber architectures were fabricated via electrospinning (Es), plastic compression and tensile (PCT), and dynamic shear stress (SS) methods. Under the observation of POM, SEM, AFM and TEM, the...