Self-sealing hemostatic and antibacterial needles by polyphenol-assisted surface self-assembly of multifunctional nanoparticles

Tissue puncture with needles is frequently applied for blood sampling, drug injection, and percutaneous biopsies. Bleeding is a critical complication following this clinical procedure, particularly in patients suffering from inherited or acquired bleeding disorders. Herein we engineered self-sealing hemostatic and antibacterial needles by facile self-assembly. In this strategy, an adhesive coating derived from polyphenols (either dopamine or...