Role of Benzo (a) Pyrene in exacerbating the skin inflammation in Psoriatic mouse model

Emerging evidence suggests that environmental chemicals, mainly the organic pollutants like polycyclic hydrocarbons (PAHs), could contribute to the pathophysiology of several chronic inflammatory skin diseases like atopic dermatitis and psoriasis. Benzo[a]pyrene (BaP), the main source of atmospheric PAH, is generated mainly from cigarette smoke, wood-burning and automobile exhaust. Several reports suggest that the inflammatory effects exerted by...