Safety and clinical outcome of tamoxifen in Duchenne muscular dystrophy
Abstract
Patients having Duchenne muscular dystrophy (DMD) are currently being treated with corticosteroids, which slow down disease progression at the expense of serious adverse effects. Tamoxifen is a pro-drug some of whose metabolites interact with the nuclear estrogen receptor, leading to anti-fibrotic and muscle-protective effects as has been demonstrated in a murine model of DMD. Here we report the results from a monocentric single arm prospective...
Paper Details
Title
Safety and clinical outcome of tamoxifen in Duchenne muscular dystrophy
Published Date
Sep 1, 2021
Journal
Volume
31
Issue
9
Pages
803 - 813
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