Optimization and application of green solvent extraction of natural bioactive coumarins from Lamiaceae and Asteraceae herbal plants

• The effect of LTTMs composition on coumarins extraction was verified. • The recovery reached higher than 87% under the optimized conditions. • Efficient method with ecological LTTM extraction and HPLC determination of coumarins was developed. Simple coumarins, 2H-1-benzopyran-2-ones, represent group of natural bioactive compounds. They are considered as secondary metabolites in plants of Lamiaceae and Asteraceae families . In this study, heat...