Peptides Derived from Palindromic Sequence RWQWRWQWR Exert an Additive Effect with Fluconazole in A Drug-Resistant C. albicans Strain
Published: May 27, 2021
Abstract
Antimicrobial resistance is a public health problem, requiring the development of new therapeutic agents. Antimicrobial peptides derived from Bovine Lactoferricin (LfcinB) have exhibited antibacterial and antifungal effects. Lipopeptides and peptides containing non-natural amino acids, derived from LfcinB (21-25) Pal: RWQWRWQWR, were synthesized by SPPS-Fmoc/tBu and characterized by RP-HPLC and MALDI-TOF mass spectrometry. The antimicrobial...
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