Cisplatin induces differentiation in teratomas derived from pluripotent stem cells
Abstract
Currently, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be induced to differentiate at the cellular level but not to form mature tissues or organs suitable for transplantation. ESCs/iPSCs form immature teratomas after injection into immunodeficient mice. In humans, immature teratomas often transform into fully differentiated mature teratomas after administration of anticancer agents.We first investigated the ability...
Paper Details
Title
Cisplatin induces differentiation in teratomas derived from pluripotent stem cells
Published Date
Dec 1, 2021
Journal
Volume
18
Pages
117 - 126
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Notes
History